Antimicrobial and cytostatic activity of biosynthesized nanogold prepared using fruit extract of Ribes nigrum

Renata Dobrucka , Joanna Dlugaszewska , Mariusz Kaczmarek

Abstract

In the present work, we report the biosynthesis of Au nanoparticles using fruit extract of Ribes nigrum. First, the synthesis of gold nanoparticles was performed, and then the structural characteristics, antimicrobial activity and cytotoxicity were assessed. The structural properties of biosynthesized gold nanoparticles were characterized by UV–Vis spectroscopy, Atomic Force Microscopy (AFM) measurements, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Fourier Transform Infrared Spectroscopy (FTIR). The antimicrobial properties of synthesized Au nanoparticles were tested against standard and clinical strains of bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli), yeast (Candida albicans) and filamentous fungi (Aspergillus niger, Trichophyton rubrum). The conducted studies constitute the basis for further investigations of the potential use of nanogold as chemotherapeutics.
Author Renata Dobrucka (WT / KTiEPP)
Renata Dobrucka,,
- Department of Industrial Products and Ecology
, Joanna Dlugaszewska - Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
Joanna Dlugaszewska,,
-
, Mariusz Kaczmarek - Poznań University of Medical Sciences
Mariusz Kaczmarek,,
-
Journal seriesArabian Journal of Chemistry, ISSN 1878-5352, e-ISSN 1878-5379, (N/A 70 pkt)
Issue year2019
Vol12
No8
Pages3902-3910
Publication size in sheets0.5
Keywords in Polishbiosynteza, nanozłoto, aktywność przeciwdrobnoustrojowa, aktywność cytostatyczna
Keywords in EnglishBiosynthesis, Gold nanoparticles, Antimicrobial activity, Cytostatic activity
ASJC Classification1500 General Chemical Engineering; 1600 General Chemistry
DOIDOI:10.1016/j.arabjc.2016.02.009
URL https://www.sciencedirect.com/science/article/pii/S1878535216000344
Languageen angielski
Score (nominal)70
Score sourcejournalList
ScoreMinisterial score = 70.0, 03-04-2020, ArticleFromJournal
Publication indicators WoS Citations = 1; Scopus SNIP (Source Normalised Impact per Paper): 2018 = 1.554; WoS Impact Factor: 2018 = 3.298 (2) - 2018=4.039 (5)
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UwagiFirst online 24 February 2016
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