Cytotoxic and antimicrobial effect of biosynthesized silver nanoparticles using the fruit extract ofRibes nigrum

Renata Dobrucka , Mariusz Kaczmarek , Jolanta Dlugaszewska


The present study reveals the efficiency of the fruit extract of Ribes nigrum in the green synthesis of silver nanoparticles (Ag-NPs). Biosynthesized Ag-NPs were characterized by UV-vis, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and atomic force microscopy (AFM). The nanoparticles were found to be 5 – 10 nm. In some places, the particles were agglomerated. The nanoparticles showed strong bactericidal activity and fungicidal activity against dermatophytes Trichophyton rubrum ATCC 28188. Moreover, the A549 and CCD39Lu cells under the influence of the highest concentration of nanoparticles synthesized using the fruit extract of Ribes nigrum showed the maximum mortality. Also, the results indicate that Ag-NPs synthesized using the fruit extract of Ribes nigrum exhibit efficiency in therapy of human non- small cell lung cancer A549.
Author Renata Dobrucka (WT / KTiEPP)
Renata Dobrucka,,
- Department of Industrial Products and Ecology
, Mariusz Kaczmarek
Mariusz Kaczmarek,,
, Jolanta Dlugaszewska
Jolanta Dlugaszewska,,
Journal seriesAdvances in Natural Sciences-Nanoscience and Nanotechnology, ISSN 2043-6254, (A 25 pkt)
Issue year2018
Publication size in sheets0.5
Keywords in Englishbiosynthesis, silver nanopartilces, antimicrobial activity, anticancer activity
Languageen angielski
Score (nominal)25
Score sourcejournalList
ScoreMinisterial score = 25.0, 24-03-2020, ArticleFromJournal
Publication indicators WoS Citations = 0; WoS Impact Factor: 2015 = 1.581 (2)
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