Surface and Antimicrobial Activity of Sulfobetaines

Daria Wieczorek , Daniela Gwiazdowska , Katarzyna Staszak , Ying-Lien Chen , Tang-Long Shen


Sulfobetaines belong to the group of zwitterionic surfactants. They are electroneutral salts, which have in the same molecule, two ionic centers with different charge. Due to the specific structure they exhibit excellent properties such as good solubility in water and detergency. In this paper we present surface properties and adsorption parameters of sulfobetaines in water/air systems. From the adsorption isotherms the CMC value, the surface tension and surface pressure at the CMC as well as the efficiency of adsorption were determined. Physicochemical analyses of the data allowed for the further description of adsorption process. Results showed that sulfobetaines exhibit good surface properties especially low CMC and p20 values. Additionally the antimicrobial activity of sulfobetaines solutions against gram‐positive and gram‐negative bacteria were tested by the well‐diffusion method. MIC values and growth kinetics were determined by microdilution method. Antimicrobial assays demonstrated that sulfobetaines can be good antibacterial agents, but the activity of surfactants strongly depends on alkyl chain length.
Author Daria Wieczorek (WT / KTiAI)
Daria Wieczorek,,
- Department of Technology and Instrumental Analysis
, Daniela Gwiazdowska (WT / KPPJ)
Daniela Gwiazdowska,,
- Department of Natural Science and Quality Assurance
, Katarzyna Staszak - Politechnika Poznańska (PP), MNiSW [80]
Katarzyna Staszak,,
, Ying-Lien Chen - National Taiwan University
Ying-Lien Chen ,,
, Tang-Long Shen - National Taiwan University
Tang-Long Shen ,,
Journal seriesJournal of Surfactants and Detergents, ISSN 1097-3958, (A 25 pkt)
Issue year2016
Publication size in sheets0.5
Keywords in EnglishSulfobetaine, Antimicrobial activity, Surface activity, Surfactant, MIC
ASJC Classification1500 General Chemical Engineering; 1606 Physical and Theoretical Chemistry; 2508 Surfaces, Coatings and Films
Languageen angielski
Score (nominal)25
Score sourcejournalList
ScoreMinisterial score = 25.0, 10-01-2020, ArticleFromJournal
Ministerial score (2013-2016) = 25.0, 10-01-2020, ArticleFromJournal
Publication indicators WoS Citations = 5; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 0.884; WoS Impact Factor: 2016 = 1.45 (2) - 2016=1.7 (5)
Citation count*16 (2021-06-17)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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